Deoxynivalenol (DON)
Type B trichothecene mycotoxin used in food and feed safety research, analytical method development, LC-MS/MS calibration, HPLC validation, and diagnostic assay development.
Also known as: DON; Vomitoxin; Deoxynivalenol standard; DON reference material
Pack sizes and catalogue pricing
| Pack size | Catalogue price | |
|---|---|---|
| 1 mg | USD $45.00 | Add to cart |
| 10 mg | USD $195.00 | Add to cart |
| 100 mg | USD $1,095.00 | Add to cart |
Prices are shown in USD; Canadian customers are quoted in CAD. Shipping is quoted per destination after the order is placed, and an order stays in a single currency from product price through final total and payment.
Source and origin
A type B trichothecene produced by Fusarium species, principally Fusarium graminearum and Fusarium culmorum, the fungi responsible for Fusarium head blight in wheat, barley and maize. TripleBond manufactures this material by controlled fermentation at its Canadian laboratory, followed by in-house extraction and purification.
Physical and chemical properties
| Appearance | White to off-white crystalline solid |
|---|---|
| Molecular formula | C15H20O6 |
| Molecular weight | 296.32 g/mol |
| Purity | 98% |
Solubility
Soluble in methanol, acetonitrile, ethanol and ethyl acetate. Also appreciably soluble in water, which distinguishes it from many other mycotoxins. Poorly soluble in non-polar solvents such as hexane.
Storage and stability
Recommended storage: −20 °C, protected from light and moisture. Allow the vial to reach room temperature before opening to avoid condensation. Prepare stock solutions in a suitable organic solvent and store sealed at −20 °C.
Applications
LC-MS/MS and GC-MS calibration, HPLC method development and validation, ELISA and lateral-flow kit development, cereal and animal-feed surveillance, proficiency testing, reference material preparation, and toxicology and metabolism research.
Safety and handling
Bulk and kilogram-scale supply
Bulk requirements are quoted individually: purity specification, packaging, lead time and recurring supply are agreed for each project. Send a bulk enquiry with the quantity and application, and we will come back with feasibility, lead time and pricing.
Programmes that start small and will need to scale can follow our scale-up pathway, from development quantities through a pilot batch to production supply, with the specification and supply plan agreed at each stage.
Quality
Deoxynivalenol (DON) is produced at TripleBond's own Canadian laboratory, which operates under PHAC Containment Level 2 and CFIA PPC-1 conditions with an ISO 9001:2015 controlled quality-management system. Identity is confirmed and each batch is released after internal analytical review.
Frequently asked questions
- Who manufactures Deoxynivalenol (DON)?
- TripleBond Scientific Inc., at its own laboratory in Guelph, Ontario, Canada. You buy direct from the manufacturer.
- Can Deoxynivalenol (DON) be supplied in bulk, at gram or kilogram scale?
- TripleBond manufactures beyond the milligram quantities most reference-material suppliers stop at. Gram and kilogram-scale requirements, recurring supply programmes and custom synthesis projects are set up per project: feasibility, lead time and specification are confirmed for the specific compound and quantity. Programmes that will need to scale can follow our scale-up pathway from development quantities to production supply.
- Do you ship internationally?
- Yes, worldwide from Canada, subject to documentation and regulatory requirements for the destination. Shipping is quoted per destination before any payment is requested.